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Sowjanya, M.
- Evaluation of Anti-bacterial and Anti-inflammatory Activities of Ethanolic Extract of Hibiscus hirtus Linn. Leaves
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Authors
Affiliations
1 Department of Chemistry, A.K.R.G. College of Pharmacy, Nallajerla, Andhra Pradesh, IN
2 Dept. of Pharmacology, Brilliant Group of Institutions, Abdullapaur, R.R. Dist., Hyderabad, Telangana, IN
3 Department of Analysis, A.K.R.G. College of Pharmacy, Nallajerla, Andhra Pradesh, IN
4 Vijaya Teja Degree College, Addanki, Andhra Pradesh, IN
1 Department of Chemistry, A.K.R.G. College of Pharmacy, Nallajerla, Andhra Pradesh, IN
2 Dept. of Pharmacology, Brilliant Group of Institutions, Abdullapaur, R.R. Dist., Hyderabad, Telangana, IN
3 Department of Analysis, A.K.R.G. College of Pharmacy, Nallajerla, Andhra Pradesh, IN
4 Vijaya Teja Degree College, Addanki, Andhra Pradesh, IN
Source
Asian Journal of Pharmaceutical Research, Vol 12, No 1 (2022), Pagination: 5 - 10Abstract
The current investigation is started to find the antibacterial and anti-inflammatory activities of the sub shrub Hibiscus hirtus L. The leaves of this conventional shrub were found to possess' different activities which incorporate antibacterial and hostile to helminthic effects. Thus we made an endeavor to perform extraction utilizing ethanol as solvent and soxhlation as a strategy for extraction. The leaves were priorly researched for their pharmacognostic, phytochemical and physical parameters. The antibacterial action of the ethanolic leaf extract was conveyed at various concentrations on strains of gram positive and gram-negative bacteria, for example, Staphylococcus aureus and Escherechia coli individually by utilizing cup and plate technique. The outcomes were outfitted as the zone of inbition acquired around every grouping of the concentrate and were compared with those of standard antibiotic utilized in the analysis, amoxycillin. Anti-inflammatory activity of Hibiscus hirtus L was studied and compared with standard drug, ibuprofen. Ethanollic concentrate of leaves (2.5- 15 mg/ml) and ibuprofen (2.5-15 mg/ml) were utilized to measure the paw edema by plethysmometer and compared with control groups. Hibiscus hirtus L showed critical decrease of paw edema in the chosen model of inflammation for example formalin prompted chronic model of inflammation. Ethanollic concentrate of the plant leaves showed anti- microbial and anti-inflammatory impacts.
Keywords
Hibiscus hirtus L, Anti-inflammatory, Antimicrobial activity, Extraction
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- In-Vitro Screening Of Anti-Microbial, Anti-Fungal And Anti-Oxidant Activities Of Ethanolic Leaf Extract Of Anthocephalus cadamba
Abstract Views :155 |
PDF Views:0
Authors
Nalla Priyanka
1,
M. Srikanth
2,
Raveendra Babu
3,
M. Sowjanya
4,
V . Ramya Sri
1,
M. Vasanthi
1,
K. Sri Lakshmi Bhargavi
1,
Y. Tirupathaiah
1,
K. Mohana Sri Vasavi
1,
N. Raviteja
1
Affiliations
1 Department of Pharmaceutical Chemistry, A.K.R.G. College of Pharmacy, Nallajerla, W.G. Dist., Andhra Pradesh, IN
2 Department of Pharmacognosy, A.K.R.G. College of Pharmacy, Nallajerla, W.G. Dist., Andhra Pradesh, IN
3 Department of Pharmaceutical Analysis, A.K.R.G. College of Pharmacy, Nallajerla, W.G. Dist., Andhra Pradesh, IN
4 Department of Chemistry, Vijaya Teja Degree College, Addanki - 523201, Andhra Pradesh, IN
1 Department of Pharmaceutical Chemistry, A.K.R.G. College of Pharmacy, Nallajerla, W.G. Dist., Andhra Pradesh, IN
2 Department of Pharmacognosy, A.K.R.G. College of Pharmacy, Nallajerla, W.G. Dist., Andhra Pradesh, IN
3 Department of Pharmaceutical Analysis, A.K.R.G. College of Pharmacy, Nallajerla, W.G. Dist., Andhra Pradesh, IN
4 Department of Chemistry, Vijaya Teja Degree College, Addanki - 523201, Andhra Pradesh, IN
Source
Asian Journal of Pharmaceutical Research, Vol 12, No 4 (2022), Pagination: 275 - 280Abstract
Anthocephalus cadamba, Rubiaceae, is a medicinal herb of great importance for traditional applications against several disease kinds. Because of the range of compounds, the genus Anthocephalus is regarded as one of the most significant genus utilised in many medical systems. The plant was chemically investigated for its phytoconstituents in the current analysis, Anthocephalus cadamba. The results for steroids, flavanoids, tannins and glycosides were shown to be positive. Bacterial species, such as Staphylococcus aureus, Bacillus subtiliis and Escherichia coli, have been moderately actively monopolised. Antifungal activity at doses of 100mg/ml, 300mg/ml with fungal organisms, was observed in the ethanol leaves extract. Plant ethanol extract had a substantial impact on the hydrogen peroxide radical activity of scavenging and less effects than the standard of nitric oxide radical activity.
Keywords
Anthocephalus cadamba, Scavenging activity, Anti microbial activity, Gram + VeReferences
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